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เพิ่ม:1002, เฮือนเมา อาคาร No.105, เหมิงเฉิง ถนน เหอเฟย์ เมือง 230061, จีน

CAS NO:162012-67-1
Molecular Formula:C14H7ClF2N4O2
Molecular Weight: 336.681
EINECS NO: N/A
MDL NO: MFCD09998825
Product Description
Product Name: 4-(3-chloro-4-fiuoro-phenylaMino)-7-fluoro-6-nitroquninazoline CAS NO:162012-67-1
Synonyms:
4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-;
N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine;
N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine;
Chemical & Physical Properties
Appearance :Yellow powder.
Assay : ≥99.0%, EE ≥99.5%
Density: 1.617 g/cm3
Boiling Point:488.589℃ at 760 mmHg
Flash Point:249.29℃
Refractive Index: 1.707
Vapor Pressure: 0mmHg at 25°C
4-(3-Chloro-4-fluorophenylamino)-7-fluoro-6-nitroquninazoline is an intermediate in the synthesis of Afatinib, an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
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