Polyinosinic–polycytidylic Acid Sodium Salt(Poly IC) (PIC) CAS 24939-03-5

Product Description:

Product Name: Polyinosinic–polycytidylic acid sodium salt(Poly IC) (PIC) CAS NO: 24939-03-5

 

Synonyms:

polyri:polyrc;

polyi:c;

Poly(I).Poly(C);

 

Chemical Physical Properties:

Appearance: Powder

Assay : Greater than or equal to 99.0 percent

Boiling Point: 851.4 degree at 760 mmHg

Storage Condition: -20 degree

Vapor Pressure: 7.7E-31mmHg at 25 degree

 

Safety Information:

WGK Germany: 3

RTECS: TR0175000

 

Polyinosinic:polycytidylic acid (usually abbreviated poly I:C) is an immunostimulant. It is used in the form of its sodium salt to simulate viral infections.

Poly I:C is known to interact with toll-like receptor 3 (TLR3), which is expressed in the membrane of B-cells, macrophages and dendritic cells. Poly I:C is structurally similar to double-stranded RNA, which is present in some viruses and is a "natural" stimulant of TLR3. Thus, Poly I:C can be considered a synthetic analog of double-stranded RNA and is a common tool for scientific research on the immune system.

 

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